Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities

نویسندگان

چکیده

Polyomavirus-related infections are ubiqutious in immunocompromised individuals, and some cases intractable fatal. Due to a lack of approved drugs treat polyomavirus infections, cidofovir, phosphonate nucleotide analog cytomegalovirus has been repurposed as an antipolyomavirus agent.

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2021

ISSN: ['0066-4804', '1070-6283', '1098-6596']

DOI: https://doi.org/10.1128/aac.01641-20